Specific cancer stem cell-therapy by albumin nanoparticles functionalized with CD44-mediated targeting

Specific cancer stem cell-therapy by albumin nanoparticles functionalized with CD44-mediated targeting

Abstract Background Cancer stem cells (CSCs) are highly proliferative and tumorigenic, which contributes to chemotherapy resistance and tumor occurrence. CSCs specific therapy may achieve excellent therapeutic effects, especially to the drug-resistant tumors. Results In this study, we developed a ki...

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Bibliographic Details
Main Authors: Yuanyuan Li, Sanjun Shi, Yue Ming, Linli Wang, Chenwen Li, Minghe Luo, Ziwei Li, Bin Li, Jianhong Chen
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Nanobiotechnology
Subjects:
Cancer stem cells
Hyaluronic acid
CD44
Cationic albumin
All-trans-retinoic acid
Online Access:http://link.springer.com/article/10.1186/s12951-018-0424-4

Internet

http://link.springer.com/article/10.1186/s12951-018-0424-4

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