Enoxaparin sodium bone cement plays an anti-inflammatory immunomodulatory role by inducing the polarization of M2 macrophages

Abstract Objective The implantation of PMMA bone cement results in an immune response and the release of PMMA bone cement particles causes an inflammatory cascade. Our study discovered that ES-PMMA bone cement can induce M2 polarization of macrophages, which has an anti-inflammatory immunomodulatory...

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Bibliographic Details
Main Authors: Weiye Fan, Dehao Fu, Li Zhang, Zhihang Xiao, Xiaoyu Shen, Jianchao Chen, Xiangbei Qi
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-03865-8