Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions
Escaping aversive stimuli is essential for complex organisms, but prolonged exposure to stress leads to maladaptive learning. Stress alters neuronal activity and neuromodulatory signaling in distributed networks, modifying behavior. Here, we describe changes in dopaminergic neuron activity and signa...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/64041 |