Unleashing the potential of catalytic RNAs to combat mis-spliced transcripts

Unleashing the potential of catalytic RNAs to combat mis-spliced transcripts

Human transcriptome can undergo RNA mis-splicing due to spliceopathies contributing to the increasing number of genetic diseases including muscular dystrophy (MD), Alzheimer disease (AD), Huntington disease (HD), myelodysplastic syndromes (MDS). Intron retention (IR) is a major inducer of spliceopat...

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Bibliographic Details
Main Authors: Bashayer A. Khalifah, Shareefa A. Alghamdi, Ali H. Alhasan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
intron retention
synthetic biology
spliceosome
spliceopathies
catalytic RNAs
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1244377/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1244377/full

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