Pharmacogenetics of Donepezil and Memantine in Healthy Subjects

Pharmacogenetics of Donepezil and Memantine in Healthy Subjects

Donepezil and memantine are the most common drugs used for Alzheimer’s disease. Their low effectiveness could partly be explained by genetic factors. Thus, we aim to identify Single Nucleotide Polymorphisms (SNPs) associated with pharmacokinetics, pharmacodynamics, and the safety of donepezil and me...

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Bibliographic Details
Main Authors: María C. Ovejero-Benito, Dolores Ochoa, Teresa Enrique-Benedito, Miriam del Peso-Casado, Pablo Zubiaur, Marcos Navares, Manuel Román, Francisco Abad-Santos
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Personalized Medicine
Subjects:
Alzheimer
pharmacogenomics
pharmacogenetic array
pharmacokinetics
anticholinergic drugs
personalized medicine
Online Access:https://www.mdpi.com/2075-4426/12/5/788

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https://www.mdpi.com/2075-4426/12/5/788

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