Detection of Interfractional Morphological Changes in Proton Therapy: A Simulation and In Vivo Study With the INSIDE In-Beam PET

Detection of Interfractional Morphological Changes in Proton Therapy: A Simulation and In Vivo Study With the INSIDE In-Beam PET

In particle therapy, the uncertainty of the delivered particle range during the patient irradiation limits the optimization of the treatment planning. Therefore, an in vivo treatment verification device is required, not only to improve the plan robustness, but also to detect significant interfractio...

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Bibliographic Details
Main Authors: Elisa Fiorina, Veronica Ferrero, Guido Baroni, Giuseppe Battistoni, Nicola Belcari, Niccolo Camarlinghi, Piergiorgio Cerello, Mario Ciocca, Micol De Simoni, Marco Donetti, Yunsheng Dong, Alessia Embriaco, Marta Fischetti, Gaia Franciosini, Giuseppe Giraudo, Aafke Kraan, Francesco Laruina, Carmela Luongo, Davide Maestri, Marco Magi, Giuseppe Magro, Etesam Malekzadeh, Carlo Mancini Terracciano, Michela Marafini, Ilaria Mattei, Enrico Mazzoni, Paolo Mereu, Riccardo Mirabelli, Alfredo Mirandola, Matteo Morrocchi, Silvia Muraro, Alessandra Patera, Vincenzo Patera, Francesco Pennazio, Alessandra Retico, Angelo Rivetti, Manuel Dionisio Da Rocha Rolo, Valeria Rosso, Alessio Sarti, Angelo Schiavi, Adalberto Sciubba, Elena Solfaroli Camillocci, Giancarlo Sportelli, Sara Tampellini, Marco Toppi, Giacomo Traini, Serena Marta Valle, Francesca Valvo, Barbara Vischioni, Viviana Vitolo, Richard Wheadon, Maria Giuseppina Bisogni
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Physics
Subjects:
proton therapy
in vivo treatment verification
in-beam pet
range monitoring
Monte Carlo simulation
adaptive therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2020.578388/full

Internet

https://www.frontiersin.org/articles/10.3389/fphy.2020.578388/full

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