A Narrative and Critical Review of Randomized-Controlled Clinical Trials on Patent Foramen Ovale Closure for Reducing the Risk of Stroke Recurrence

Patent foramen ovale (PFO) is a common cardiac anatomic variant that has been increasingly found in young (<60 years) cryptogenic stroke patients. Despite initial neutral randomized-controlled clinical trials (RCTs), there have been four recent RCTs providing consistent data in favor of the e...

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Bibliographic Details
Main Authors: Apostolos Safouris, Odysseas Kargiotis, Klearchos Psychogios, Pericles Kalyvas, Ignatios Ikonomidis, Maria Drakopoulou, Konstantinos Toutouzas, Georgios Tsivgoulis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00434/full