Benchmarking microbial DNA enrichment protocols from human intestinal biopsies

Benchmarking microbial DNA enrichment protocols from human intestinal biopsies

Shotgun metagenomic sequencing is a powerful tool for studying bacterial communities in their natural habitats or sites of infection, without the need for cultivation. However, low microbial signals in metagenomic sequencing can be overwhelmed by host DNA contamination, resulting in decreased sensit...

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Bibliographic Details
Main Authors: Dmitrij Marchukov, Jiaqi Li, Pascal Juillerat, Benjamin Misselwitz, Bahtiyar Yilmaz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Genetics
Subjects:
gut micobiome
host DNA depletion
metagemonic
phyloseq
human small intestine
microbial enrichment
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1184473/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1184473/full

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