Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression

Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression

The immune system has many sophisticated mechanisms to balance an extensive immune response. Distinct immunosuppressive cells could protect from excessive tissue damage and autoimmune disorders. Tumor cells take an advantage of those immunosuppressive mechanisms and establish a strongly immunosuppre...

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Bibliographic Details
Main Authors: Viktor Fleming, Xiaoying Hu, Rebekka Weber, Vasyl Nagibin, Christopher Groth, Peter Altevogt, Jochen Utikal, Viktor Umansky
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
myeloid-derived suppressor cells
immunosuppression
cancer immunotherapy
tumor microenvironment
therapeutic targeting
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00398/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00398/full

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