Antinociceptive effect and anti-inflammatory activity of 1,4-naphthoquinones in mice

Antinociceptive effect and anti-inflammatory activity of 1,4-naphthoquinones in mice

Aim: The ability of synthetic 1,4-naphthoquinones (1,4-NQs) to prevent adenosine triphosphate (ATP)-induced and purinergic P2X7 receptor (P2X7R) mediated inflammation in macrophage and neurodegeneration of neuronal cells in vitro was previously established. The aim of the present study was to invest...

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Bibliographic Details
Main Authors: Sergei Kozlovskiy, Evgeny Pislyagin, Ekaterina Menchinskaya, Ekaterina Chingizova, Yuri Sabutski, Sergey Polonik, Irina Agafonova, Dmitry Aminin
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2024-02-01
Series:Exploration of Neuroscience
Subjects:
p2x7 receptor
1
4-naphthoquinones
nociceptive pain
macrophages
hot plate test
paw edema
Online Access:https://www.explorationpub.com/Journals/en/Article/100635

Internet

https://www.explorationpub.com/Journals/en/Article/100635

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