Population Pharmacokinetics of Primaquine in the Korean Population

Population Pharmacokinetics of Primaquine in the Korean Population

While primaquine has long been used for malaria treatment, treatment failure is common. This study aims to develop a population pharmacokinetic model of primaquine and its metabolite, carboxyprimaquine, and examine factors influencing pharmacokinetic variability. The data was obtained from a clinica...

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Bibliographic Details
Main Authors: Woo-Yul Lee, Dong-Woo Chae, Choon-Ok Kim, Sang-Eun Lee, Yee-Gyung Kwak, Joon-Sup Yeom, Kyung-Soo Park
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
primaquine
pharmacokinetics
CYP2D6
carboxy-primaquine
malaria
population pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/13/5/652

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https://www.mdpi.com/1999-4923/13/5/652

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