Mitochondrial metabolism in neural stem cells and implications for neurodevelopmental and neurodegenerative diseases

Mitochondrial metabolism in neural stem cells and implications for neurodevelopmental and neurodegenerative diseases

Abstract Mitochondria are cytoplasmic organelles having a fundamental role in the regulation of neural stem cell (NSC) fate during neural development and maintenance. During embryonic and adult neurogenesis, NSCs undergo a metabolic switch from glycolytic to oxidative phosphorylation with a rise in...

Full description

Bibliographic Details
Main Authors: C. Garone, F. De Giorgio, S. Carli
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
Mitochondrial metabolism
Neurodegenerative disorders
Neuronal development
Stem cells
Wnt
HIF-1A
Online Access:https://doi.org/10.1186/s12967-024-05041-w

Internet

https://doi.org/10.1186/s12967-024-05041-w

Similar Items