A folding pathway-dependent score to recognize membrane proteins.

While various approaches exist to study protein localization, it is still a challenge to predict where proteins localize. Here, we consider a mechanistic viewpoint for membrane localization. Taking into account the steps for the folding pathway of α-helical membrane proteins and relating biophysical...

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Bibliographic Details
Main Authors: Hamid Hadi-Alijanvand, Maryam Rouhani, Elizabeth A Proctor, Nikolay V Dokholyan, Ali A Moosavi-Movahedi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3046963?pdf=render