Acetylcholine Release Inhibits Distinct Excitatory Inputs Onto Hippocampal CA1 Pyramidal Neurons via Different Cellular and Network Mechanisms

Acetylcholine Release Inhibits Distinct Excitatory Inputs Onto Hippocampal CA1 Pyramidal Neurons via Different Cellular and Network Mechanisms

In hippocampal CA1, muscarinic acetylcholine (ACh) receptor (mAChR) activation via exogenous application of cholinergic agonists has been shown to presynaptically inhibit Schaffer collateral (SC) glutamatergic inputs in stratum radiatum (SR), and temporoammonic (TA) and thalamic nucleus reuniens (RE...

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Bibliographic Details
Main Authors: Priyodarshan Goswamee, A. Rory McQuiston
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
acetylcholine release
excitatory input modulation
CA1
interneurons
GABAB
GIRK channels
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00267/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00267/full

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