The role of lipid peroxidation in epithelial–mesenchymal transition of retinal pigment epithelial cells

The role of lipid peroxidation in epithelial–mesenchymal transition of retinal pigment epithelial cells

Abstract Epithelial–Mesenchymal Transition (EMT) of retinal pigment epithelial (RPE) cells is recognized as pivotal in various retinal diseases. Previous studies have suggested a reciprocal regulation between reactive oxygen species (ROS) and EMT, though the involvement of peroxidized lipids or the...

Full description

Bibliographic Details
Main Authors: Wang You, Kunihiro Azuma, Toshiro Iwagawa, Sumiko Watanabe, Makoto Aihara, Tomoyasu Shiraya, Takashi Ueta
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Scientific Reports
Subjects:
Epithelial–mesenchymal transition
Lipid peroxidation
Retinal pigment epithelium
Ferrostatin-1
ARPE-19
Online Access:https://doi.org/10.1038/s41598-024-67587-5

Internet

https://doi.org/10.1038/s41598-024-67587-5

Similar Items