Upper Tract Urothelial Carcinoma: A Rare Malignancy with Distinct Immuno-Genomic Features in the Era of Precision-Based Therapies

Upper tract urothelial carcinoma (UTUC) is a rare malignancy, occurring in 5–10% of patients diagnosed with UC, and involves the renal pelvis, calyces, or ureters. UTUC can be sporadic or hereditary as a clinical manifestation of Lynch syndrome. Therapeutic management of these patients is challengin...

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Bibliographic Details
Main Authors: Konstantinos Evmorfopoulos, Lampros Mitrakas, Athanasios Karathanasis, Ioannis Zachos, Vassilios Tzortzis, Panagiotis J. Vlachostergios
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/7/1775