Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus

Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus

Systemic lupus erythematosus (SLE) represents a challenging autoimmune disease from a clinical perspective because of its varied forms of presentation. Although broad-spectrum steroids remain the standard treatment for SLE, they have many side effects and only provide temporary relief from the sympt...

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Bibliographic Details
Main Authors: Steve P. Crampton, Peter A. Morawski, Silvia Bolland
Format: Article
Language:English
Published: The Company of Biologists 2014-09-01
Series:Disease Models & Mechanisms
Subjects:
Lupus
SLE
Human genetics
Mouse models
Susceptibility genes
Online Access:http://dmm.biologists.org/content/7/9/1033

Internet

http://dmm.biologists.org/content/7/9/1033

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