Embryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome

Embryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome

Abstract Despite the high prevalence of Down syndrome (DS) and early identification of the cause (trisomy 21), its molecular pathogenesis has been poorly understood and specific treatments have consequently been practically unavailable. A number of medical conditions throughout the body associated w...

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Bibliographic Details
Main Authors: Yanyan Liu, Ziyuan Lin, Ying Peng, Yan Jiang, Xuan Zhang, Hongmei Zhu, Lili Zhang, Jiurong Chen, Xianghua Shu, Min Luo, Dan Xie, Yan Chen, Huijuan Liao, Mingfeng Liu, Xiaohu Zhang, Shanling Liu, He Wang, Bin Zhou, Huaqin Sun
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05517-x

Internet

https://doi.org/10.1038/s41419-022-05517-x

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