Sodium houttuyfonate enhances the mono-therapy of fluconazole on oropharyngeal candidiasis (OPC) through HIF-1α/IL-17 axis by inhibiting cAMP mediated filamentation in Candida albicans-Candida glabrata dual biofilms

Sodium houttuyfonate enhances the mono-therapy of fluconazole on oropharyngeal candidiasis (OPC) through HIF-1α/IL-17 axis by inhibiting cAMP mediated filamentation in Candida albicans-Candida glabrata dual biofilms

Candida albicans and Candida glabrata are two common opportunistic fungi that can be co-isolated in oropharyngeal candidiasis (OPC). Hypha is a hallmark of the biofilm formation of C. albicans, indispensable for the attachment of C. glabrata, which is seldom in mycelial morphology. Increasing eviden...

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Bibliographic Details
Main Authors: Mengli Chen, Ting Cheng, Chen Xu, Min Pan, Jiadi Wu, Tianming Wang, Daqiang Wu, Guiming Yan, Changzhong Wang, Jing Shao
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Virulence
Subjects:
candida albicans
candida glabrata
mixed biofilms
hypoxia
sodium houttuyfonate
oropharyngeal candidiasis
Online Access:http://dx.doi.org/10.1080/21505594.2022.2035066

Internet

http://dx.doi.org/10.1080/21505594.2022.2035066

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