Orexin Neurons Contribute to Central Modulation of Respiratory Drive by Progestins on ex vivo Newborn Rodent Preparations

Orexin Neurons Contribute to Central Modulation of Respiratory Drive by Progestins on ex vivo Newborn Rodent Preparations

Dysfunction of central respiratory CO2/H+ chemosensitivity is a pivotal factor that elicits deep hypoventilation in patients suffering from central hypoventilation syndromes. No pharmacological treatment is currently available. The progestin desogestrel has been suggested to allow recovery of respir...

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Bibliographic Details
Main Authors: Camille Loiseau, Alexis Casciato, Besma Barka, Florence Cayetanot, Laurence Bodineau
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Physiology
Subjects:
CO2/H+ chemosensitivity
congenital central hypoventilation syndrome
etonogestrel
ex vivo central nervous system preparation
orexin
progestin
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01200/full

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https://www.frontiersin.org/article/10.3389/fphys.2019.01200/full

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