Reducing Epistasis and Pleiotropy Can Avoid the Survival of the Flattest Tragedy

This study investigates whether reducing epistasis and pleiotropy enhances mutational robustness in evolutionary adaptation, utilizing an indirect encoded model within the “survival of the flattest” (SoF) fitness landscape. By simulating genetic variations and their phenotypic consequences, we explo...

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Bibliographic Details
Main Authors: Priyanka Mehra, Arend Hintze
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/13/3/193