Single-cell analysis of transcriptome and DNA methylome in human oocyte maturation.

Oocyte maturation is a coordinated process that is tightly linked to reproductive potential. A better understanding of gene regulation during human oocyte maturation will not only answer an important question in biology, but also facilitate the development of in vitro maturation technology as a fert...

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Bibliographic Details
Main Authors: Bo Yu, Naresh Doni Jayavelu, Stephanie L Battle, Jessica C Mar, Timothy Schimmel, Jacques Cohen, R David Hawkins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241698