CDKs in Sarcoma: Mediators of Disease and Emerging Therapeutic Targets

CDKs in Sarcoma: Mediators of Disease and Emerging Therapeutic Targets

Sarcomas represent one of the most challenging tumor types to treat due to their diverse nature and our incomplete understanding of their underlying biology. Recent work suggests cyclin-dependent kinase (CDK) pathway activation is a powerful driver of sarcomagenesis. CDK proteins participate in nume...

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Bibliographic Details
Main Authors: Jordan L Kohlmeyer, David J Gordon, Munir R Tanas, Varun Monga, Rebecca D Dodd, Dawn E Quelle
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
cyclin-dependent kinase
sarcoma
cell cycle
therapeutics
retinoblastoma protein
CDK inhibitors
Online Access:https://www.mdpi.com/1422-0067/21/8/3018

Internet

https://www.mdpi.com/1422-0067/21/8/3018

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