Designed Amino Acid Feed in Improvement of Production and Quality Targets of a Therapeutic Monoclonal Antibody.

Cell culture feeds optimization is a critical step in process development of pharmaceutical recombinant protein production. Amino acids are the basic supplements of mammalian cell culture feeds with known effect on their growth promotion and productivity. In this study, we reported the implementatio...

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Bibliographic Details
Main Authors: Fatemeh Torkashvand, Behrouz Vaziri, Shayan Maleknia, Amir Heydari, Manouchehr Vossoughi, Fatemeh Davami, Fereidoun Mahboudi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4610691?pdf=render