Ruthenium red improves blastocyst developmental competence by regulating mitochondrial Ca2+ and mitochondrial functions in fertilized porcine oocytes in vitro

Ruthenium red improves blastocyst developmental competence by regulating mitochondrial Ca2+ and mitochondrial functions in fertilized porcine oocytes in vitro

Ruthenium red (RR) inhibits calcium (Ca2+) entry from the cytoplasm to the mitochondria, and is involved in maintenance of Ca2+ homeostasis in mammalian cells. Ca2+ homeostasis is very important for further embryonic development of fertilized oocytes. However, the effect of RR on mitochondria-Ca2+ (...

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Bibliographic Details
Main Authors: Ho-Geun JEGAL, Hyo-Jin PARK, Jin-Woo KIM, Seul-Gi YANG, Min-Ji KIM, Deog-Bon KOO
Format: Article
Language:English
Published: The Society for Reproduction and Development 2020-04-01
Series:The Journal of Reproduction and Development
Subjects:
in vitro fertilization
mito-ca2+ uptake 1 (micu1)
mitochondria-ca2+
porcine embryos
ruthenium red
Online Access:https://www.jstage.jst.go.jp/article/jrd/66/4/66_2020-013/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/jrd/66/4/66_2020-013/_pdf/-char/en

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