Microelectrode Arrays Measure Blocking of Voltage‐Gated Calcium Ion Channels on Supported Lipid Bilayers Derived from Primary Neurons

Microelectrode Arrays Measure Blocking of Voltage‐Gated Calcium Ion Channels on Supported Lipid Bilayers Derived from Primary Neurons

Abstract Drug studies targeting neuronal ion channels are crucial to understand neuronal function and develop therapies for neurological diseases. The traditional method to study neuronal ion‐channel activities heavily relies on the whole‐cell patch clamp as the industry standard. However, this tech...

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Bibliographic Details
Main Authors: Zixuan Lu, Chiara Barberio, Ana Fernandez‐Villegas, Aimee Withers, Alexandra Wheeler, Konstantinos Kallitsis, Eleonora Martinelli, Achilleas Savva, Becky M. Hess, Anna‐Maria Pappa, Gabriele S. Kaminski Schierle, Róisín M. Owens
Format: Article
Language:English
Published: Wiley 2024-07-01
Series:Advanced Science
Subjects:
blebbing
microelectrode arrays
neurons
PEDOT:PSS
supported lipid bilayers
voltage‐gated ion channels
Online Access:https://doi.org/10.1002/advs.202304301

Internet

https://doi.org/10.1002/advs.202304301

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