Lasso Peptide Microcin J25 Effectively Enhances Gut Barrier Function and Modulates Inflammatory Response in an Enterotoxigenic <i>Escherichia coli</i>-Challenged Mouse Model

Lasso Peptide Microcin J25 Effectively Enhances Gut Barrier Function and Modulates Inflammatory Response in an Enterotoxigenic <i>Escherichia coli</i>-Challenged Mouse Model

Bacterial resistance leads to severe public health and safety issues worldwide. Alternatives to antibiotics are currently needed. A promising lasso peptide, microcin J25 (MccJ25), is considered to be the best potential substitute for antibiotics to treat pathogen infection, including enterotoxigenic...

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Bibliographic Details
Main Authors: Xiuliang Ding, Haitao Yu, Shiyan Qiao
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
enterotoxigenic <i>Escherichia coli</i>
microcin J25
intestinal epithelial barrier
intestinal inflammation
mice
pathogen
Online Access:https://www.mdpi.com/1422-0067/21/18/6500

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https://www.mdpi.com/1422-0067/21/18/6500

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