Unifying the known and unknown microbial coding sequence space

Unifying the known and unknown microbial coding sequence space

Genes of unknown function are among the biggest challenges in molecular biology, especially in microbial systems, where 40–60% of the predicted genes are unknown. Despite previous attempts, systematic approaches to include the unknown fraction into analytical workflows are still lacking. Here, we pr...

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Bibliographic Details
Main Authors: Chiara Vanni, Matthew S Schechter, Silvia G Acinas, Albert Barberán, Pier Luigi Buttigieg, Emilio O Casamayor, Tom O Delmont, Carlos M Duarte, A Murat Eren, Robert D Finn, Renzo Kottmann, Alex Mitchell, Pablo Sánchez, Kimmo Siren, Martin Steinegger, Frank Oliver Gloeckner, Antonio Fernàndez-Guerra
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
microbial genomics
bioinformatics
gene clusters
functional metageomics
phylogenomics
unknown function
Online Access:https://elifesciences.org/articles/67667

Internet

https://elifesciences.org/articles/67667

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