Cellular electrophysiological effects of the citrus flavonoid hesperetin in dog and rabbit cardiac ventricular preparations

Abstract Recent experimental data shows that hesperetin, a citrus flavonoid, affects potassium channels and can prolong the QTc interval in humans. Therefore, in the present study we investigated the effects of hesperetin on various transmembrane ionic currents and on ventricular action potentials....

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Bibliographic Details
Main Authors: Aiman Saleh A. Mohammed, Gábor Mohácsi, Muhammad Naveed, János Prorok, Norbert Jost, László Virág, István Baczkó, Leila Topal, András Varró
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-57828-y