Modeling of miRNA and drug action in the EGFR signaling pathway.

MicroRNAs have gained significant interest due to their widespread occurrence and diverse functions as regulatory molecules, which are essential for cell division, growth, development and apoptosis in eukaryotes. The epidermal growth factor receptor (EGFR) signaling pathway is one of the best invest...

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Bibliographic Details
Main Authors: Jian Li, Vikash Pandey, Thomas Kessler, Hans Lehrach, Christoph Wierling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3256223?pdf=render