Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research

Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research

ABSTRACTBackground: Elucidating epigenetic mechanisms could provide new biomarkers for disease diagnosis and prognosis. Technological advances allow genome-wide profiling of 5-hydroxymethylcytosines (5hmC) in liquid biopsies. 5hmC-Seal followed by NGS is a highly sensitive technique for 5hmC biomark...

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Bibliographic Details
Main Authors: Lu Gao, Zhou Zhang, Xiao-Long Cui, Diana West-Szymanski, Chang Ye, Chuan He, Wei Zhang, Marc Bissonnette
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Epigenetics
Subjects:
5-hydroxymethylcytosine
5hmC-Seal
cfDNA
EDTA
heparin
Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2023.2271692

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https://www.tandfonline.com/doi/10.1080/15592294.2023.2271692

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