Deciphering 3'UTR Mediated Gene Regulation Using Interpretable Deep Representation Learning

Deciphering 3'UTR Mediated Gene Regulation Using Interpretable Deep Representation Learning

Abstract The 3' untranslated regions (3'UTRs) of messenger RNAs contain many important cis‐regulatory elements that are under functional and evolutionary constraints. It is hypothesized that these constraints are similar to grammars and syntaxes in human languages and can be modeled by adv...

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Bibliographic Details
Main Authors: Yuning Yang, Gen Li, Kuan Pang, Wuxinhao Cao, Zhaolei Zhang, Xiangtao Li
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Advanced Science
Subjects:
3'UTRs
deep representation learning
m6A modification preference
mRNA subcellular localization
RNA–RBP interaction
Online Access:https://doi.org/10.1002/advs.202407013

Internet

https://doi.org/10.1002/advs.202407013

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