RasGRP1 promotes the acute inflammatory response and restricts inflammation-associated cancer cell growth

RasGRP1 promotes the acute inflammatory response and restricts inflammation-associated cancer cell growth

IL-6 and RasGRP1 have been shown to have important functions during inflammation and cancer. Here the authors propose the protein and mRNA of RasGRP1 have opposing functions by promoting IL-6 mediated acute inflammation and inhibiting inflammation-associated cancer through mRNA and protein mechanism...

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Bibliographic Details
Main Authors: Cong Wang, Xue Li, Binbin Xue, Changping Yu, Luoling Wang, Rilin Deng, Hui Liu, Zihao Chen, Yingdan Zhang, Suping Fan, Chaohui Zuo, Hungyu Sun, Haizhen Zhu, Jianli Wang, Songqing Tang
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34659-x

Internet

https://doi.org/10.1038/s41467-022-34659-x

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