Moderate LMWH Anticoagulation Improves Success Rate of Hind Limb Allotransplantation in Mice

Background:. The mouse hind limb model represents a powerful research tool in vascularized composite tissue allotransplantation, but its applicability is limited due to poor graft survival (62%–83%). Vascular thrombosis and massive hemorrhage are the major causes for these drop-outs. We hypothesize...

Full description

Bibliographic Details
Main Authors: Barbara Kern, MD, Muhammad-Imtiaz Ashraf, PhD, Anja Reutzel-Selke, PhD, Joerg Mengwasser, PhD, Dietrich Polenz, Edward Michaelis, MD, Johann Pratschke, MD, PhD, Stefan G. Tullius, MD, PhD, Christian Witzel, MD, PhD, Igor M. Sauer, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2023-09-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005249