Plasma-Based Measurements of Tumor Heterogeneity Correlate with Clinical Outcomes in Metastatic Colorectal Cancer

Plasma-Based Measurements of Tumor Heterogeneity Correlate with Clinical Outcomes in Metastatic Colorectal Cancer

Sequencing circulating tumor DNA (ctDNA) from liquid biopsies may better assess tumor heterogeneity than limited sampling of tumor tissue. Here, we explore ctDNA-based heterogeneity and its correlation with treatment outcome in STEAM, which assessed efficacy and safety of concurrent and sequential F...

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Bibliographic Details
Main Authors: Stephanie J. Yaung, Christine Ju, Sandeep Gattam, Alan Nicholas, Nicolas Sommer, Johanna C. Bendell, Herbert I. Hurwitz, John J. Lee, Fergal Casey, Richard Price, John F. Palma
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
tumor heterogeneity
intratumor heterogeneity
ctDNA
circulating tumor DNA
liquid biopsy
metastatic cancer
Online Access:https://www.mdpi.com/2072-6694/14/9/2240

Internet

https://www.mdpi.com/2072-6694/14/9/2240

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