Mathematical modeling of brain metabolites variations in the circadian rhythm

Our aim in this paper is to study ODEs models in view of applications to brain metabolites variations in the circadian rhythm. We address the well-posedness of the models, as well as the nonnegativity of the solutions. We then give numerical simulations which we compare with real medical data.

Bibliographic Details
Main Authors: Laura Hatchondo, Carole Guillevin, Mathieu Naudin, Laurence Cherfils, Alain Miranville, Rémy Guillevin
Format: Article
Language:English
Published: AIMS Press 2020-01-01
Series:AIMS Mathematics
Subjects:
Online Access:https://www.aimspress.com/article/10.3934/math.2020013/fulltext.html