Anti-inflammatory and healing action of oral gel containing borneol monoterpene in chemotherapy-induced mucositis in rats ( Rattus norvegicus )

Anti-inflammatory and healing action of oral gel containing borneol monoterpene in chemotherapy-induced mucositis in rats ( Rattus norvegicus )

ABSTRACT The aim of this study was to investigate the effect of gels containing the monoterpene borneol in induced oral mucositis using an animal model. Gels were prepared with borneol at 1.2% and 2.4% (w/w). Oral mucositis was induced by administration of three doses of 5-fluorouracil (30 mg/kg, i....

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Main Authors: Braz José do Nascimento-Júnior, Lucas de Souza Brito, Walquíria Nunes Barros, Daniela Marques Gonçalves, Luana de Souza Matos, Cínthia Reyjane Borges Nascimento, Luciano Augusto de Araújo Ribeiro, Ricardo Santana de Lima, René Geraldo Cordeiro Silva-Júnior, Sílvio Alan Gonçalves Bomfim Reis, Talita Mota Gonçalves, Elba Lúcia Cavalcanti de Amorim
Format: Article
Language:English
Published: Universidade de São Paulo 2017-07-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Chemotherapy
Oral gel/Borneol monoterpene/effects
Oral gel/Borneol monoterpene/action anti-inflammatory
Oral gel/Borneol monoterpene/healing action
Bornyl alcohol/effects
Palliative care
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300604&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300604&lng=en&tlng=en

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