Tyrosine Kinase Inhibitor Antitumor Therapy and Atrial Fibrillation: Potential Off-Target Effects on Mitochondrial Function and Cardiac Substrate Utilization

Tyrosine kinase inhibitors (TKIs) are a novel category of antitumor agents with remarkable efficacy in extending patient survival. However, clinical use of TKIs has been hindered by the major adverse effect of atrial fibrillation (AF). Recent studies have revealed that TKIs induce metabolic alterati...

Full description

Bibliographic Details
Main Authors: Yukun Li, Xiaodong Peng, Rong Lin, Xuesi Wang, Xinmeng Liu, Fanchao Meng, Yanfei Ruan, Rong Bai, Ribo Tang, Nian Liu
Format: Article
Language:English
Published: Compuscript Ltd 2023-10-01
Series:Cardiovascular Innovations and Applications
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0070