Lidocaine ameliorates chronic constriction injury-induced neuropathic pain through regulating M1/M2 microglia polarization

This study is intended to explore the mechanism that lidocaine ameliorates chronic constriction injury (CCI)-induced neuropathic pain (NP) related to the polarization of M1 and M2 microglia. CCI rats were established by surgery to induce NP. The mechanical withdrawal threshold (MWT) and thermal with...

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Bibliographic Details
Main Authors: Yuan Jiaqi, Fei Yue
Format: Article
Language:English
Published: De Gruyter 2022-05-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2022-0480