miR579-3p is an inhibitory modulator of neointimal hyperplasia and transcription factors c-MYB and KLF4

Abstract Neointimal hyperplasia (IH) is a common vascular pathology that typically manifests in in-stent restenosis and bypass vein graft failure. Smooth muscle cell (SMC) phenotypic switching is central to IH, both regulated by some microRNAs, yet the role of miR579-3p, a scarcely studied microRNA,...

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Bibliographic Details
Main Authors: Xiujie Xie, Takuro Shirasu, Jing Li, Lian-Wang Guo, K. Craig Kent
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01364-7