The Metabolic Fates of Pyruvate in Normal and Neoplastic Cells
Pyruvate occupies a central metabolic node by virtue of its position at the crossroads of glycolysis and the tricarboxylic acid (TCA) cycle and its production and fate being governed by numerous cell-intrinsic and extrinsic factors. The former includes the cell’s type, redox state, ATP content, meta...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/4/762 |