Development of an in Vitro Potency Assay for Anti-anthrax Lethal Toxin Neutralizing Antibodies

Lethal toxin (LT) of Bacillus anthracis reduces the production of a number of inflammatory mediators, including transcription factors, chemokines and cytokines in various human cell lines, leading to down-regulation of the host inflammatory response. Previously we showed that the reduction of interl...

Full description

Bibliographic Details
Main Authors: Sjoerd Rijpkema, Michael Baker, Gail Whiting
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/4/1/28/