Integrin αvβ6-targeted MR molecular imaging of breast cancer in a xenograft mouse model

Abstract Background The motif RXDLXXL-based nanoprobes allow specific imaging of integrin αvβ6, a protein overexpressed during tumorigenesis and tumor progression of various tumors. We applied a novel RXDLXXL-coupled cyclic arginine-glycine-aspartate (RGD) nonapeptide conjugated with ultrasmall supe...

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Bibliographic Details
Main Authors: Dengfeng Li, Chengyan Dong, Xiaohong Ma, Xinming Zhao
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Cancer Imaging
Subjects:
Online Access:https://doi.org/10.1186/s40644-021-00411-9