S Protein-Reactive IgG and Memory B Cell Production after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit

S Protein-Reactive IgG and Memory B Cell Production after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit

ABSTRACT The high susceptibility of humans to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the cause of coronavirus disease 2019 (COVID-19), reflects the novelty of the virus and limited preexisting B cell immunity. IgG against the SARS-CoV-2 spike (S) protein, which carri...

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Bibliographic Details
Main Authors: Phuong Nguyen-Contant, A. Karim Embong, Preshetha Kanagaiah, Francisco A. Chaves, Hongmei Yang, Angela R. Branche, David J. Topham, Mark Y. Sangster
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mBio
Subjects:
COVID-19
IgG antibodies
memory B cells
SARS-CoV-2
spike protein
Online Access:https://journals.asm.org/doi/10.1128/mBio.01991-20

Internet

https://journals.asm.org/doi/10.1128/mBio.01991-20

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