Cell surface area and membrane folding in glioblastoma cell lines differing in PTEN and p53 status.

Glioblastoma multiforme (GBM) is characterized by rapid growth, invasion and resistance to chemo-/radiotherapy. The complex cell surface morphology with abundant membrane folds, microvilli, filopodia and other membrane extensions is believed to contribute to the highly invasive behavior and therapy...

Full description

Bibliographic Details
Main Authors: Simon Memmel, Vladimir L Sukhorukov, Marcus Höring, Katherine Westerling, Vanessa Fiedler, Astrid Katzer, Georg Krohne, Michael Flentje, Cholpon S Djuzenova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3909012?pdf=render