Neurodegeneration Is Associated to Changes in Serum Insulin-like Growth Factors

Serum levels of insulin and insulin-like growth factors and their binding proteins (IGFs and IGFBPs, respectively) are changed in human neurodegenerative diseases of very different etiology, such as Alzheimer's disease, amyotrophic lateral sclerosis, or cerebellar ataxia. However, the significa...

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Bibliographic Details
Main Authors: Svetlana Busiguina, Ana M. Fernandez, Vicente Barrios, Ruth Clark, Daniel L. Tolbert, Jose Berciano, Ignacio Torres-Aleman
Format: Article
Language:English
Published: Elsevier 2000-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996100903115