Heparanase-1: From Cancer Biology to a Future Antiviral Target
Heparan sulfate proteoglycans (HSPGs) are a major constituent of the extracellular matrix (ECM) and are found to be implicated in viral infections, where they play a role in both cell entry and release for many viruses. The enzyme heparanase-1 is the only known endo-beta-D-glucuronidase capable of d...
Main Authors: | Nadjet Lebsir, Fabien Zoulim, Boyan Grigorov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/15/1/237 |
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