Immunological significance of prognostic alternative splicing signature in hepatocellular carcinoma

Immunological significance of prognostic alternative splicing signature in hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) ranks the sixth prevalent tumors with high mortality globally. Alternative splicing (AS) drives protein diversity, the imbalance of which might act an important factor in tumorigenesis. This study aimed to construct of AS-based prognostic signature...

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Bibliographic Details
Main Authors: Qianhui Xu, Hao Xu, Rongshan Deng, Nanjun Li, Ruiqi Mu, Zhixuan Qi, Yunuo Shen, Zijie Wang, Jingchao Wen, Jiaxin Zhao, Di Weng, Wen Huang
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma
Alternative splicing
Tumor immune microenvironment
Prognosis
Immunotherapy
Online Access:https://doi.org/10.1186/s12935-021-01894-z

Internet

https://doi.org/10.1186/s12935-021-01894-z

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