The frequency of A91V in the perforin gene and the effect of tumor necrosis factor-α promoter polymorphism on acquired hemophagocytic lymphohistiocytosis

The frequency of A91V in the perforin gene and the effect of tumor necrosis factor-α promoter polymorphism on acquired hemophagocytic lymphohistiocytosis

Objective: Numerous acquired etiological factors, such as infections, malignancies, and collagen tissue disorders, are involved in the development of acquired hemophagocytic lymphohistiocytosis (AHLH). Not everyone with the same etiological factors developments AHLH, which suggests the role of addit...

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Bibliographic Details
Main Authors: Hamza Okur, Şule Ünal, Günay Balta, Didem Efendioğlu, Eren Çimen, Mualla Çetin, Aytemiz Gürgey, Çiğdem Altay, Fatma Gümrük
Format: Article
Language:English
Published: Galenos Publishing House 2011-06-01
Series:Turkish Journal of Hematology
Subjects:
Acquired hemophagocytic lymphohistiocytosis
infection-related HLH
perforin
A91V mutation
TNF-α polymorphism
Online Access:http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-60252

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http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-60252

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