R1ρ dispersion in white matter correlates with quantitative metrics of cognitive impairment

R1ρ dispersion in white matter correlates with quantitative metrics of cognitive impairment

Much previous neuroimaging research in Alzheimer’s disease has focused on the roles of amyloid and tau proteins, but recent studies have implicated microvascular changes in white matter as early indicators of damage related to later dementia. We used MRI to derive novel, non-invasive measurements of...

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Bibliographic Details
Main Authors: Fatemeh Adelnia, Larry T. Davis, Lealani Mae Acosta, Amanda Puckett, Feng Wang, Zhongliang Zu, Kevin D. Harkins, John C. Gore
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
MRI
R1ρ dispersion imaging
Microvascular impairment
Cognitive abilities
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158223000554

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http://www.sciencedirect.com/science/article/pii/S2213158223000554

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